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These multiple biochemical reactions converge to assist the movement of intracellular vesicles containing facilitative glucose transporters to the cell membrane. In the absence of insulin, these transport proteins are usually recycled slowly between the cell membrane and cell interior. Insulin triggers the rapid movement of a pool of glucose transporter vesicles to the cell membrane, where they fuse and expose the glucose transporters to the extracellular fluid. The transporters then move glucose by facilitated diffusion into the cell interior. Visit this link to view an animation describing the situation and function of the pancreas. What goes wrong in the perform of insulin in type 2 diabetes? Insulin also reduces Healthy Flow Blood support glucose levels by stimulating glycolysis, the metabolism of glucose for era of ATP. Moreover, it stimulates the liver to transform excess glucose into glycogen for storage, and it inhibits enzymes involved in glycogenolysis and gluconeogenesis. Finally, insulin promotes triglyceride and protein synthesis. The secretion of insulin is regulated through a damaging suggestions mechanism. |
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